A duodenal ulcer is a sore in the lining of the intestine. The first part of the small intestine, just past the stomach, is called the duodenum.
Treatment may include antibiotics, medications that heal the ulcer and protect the intestine, and lifestyle changes. Surgery may be needed for ulcers that bleed, obstruct, perforate, or don't heal with other treatments.
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Upsets in the balance of stomach acid and digestive juices can lead to an ulcer. This can be caused by:
Less common causes include:
Factors that increase your chances of duodenal ulcer include:
Duodenal ulcers do not always cause symptoms. Symptoms may come and go. Food or fluids sometimes make symptoms better. Having an empty stomach may make symptoms worse. However, symptoms can occur at any time.
Symptoms may include:
Ulcers can cause serious problems and severe abdominal pain. One problem is bleeding. Bleeding symptoms may include:
A perforated ulcer is a break through the wall of the duodenum. It causes sudden and severe pain.
Your doctor will ask about your symptoms and medical history. A physical exam will be done.
Tests may include:
Talk to your doctor about the best treatment plan for you. Treatment options may include one or more of the following:
Your doctor may recommend:
You and your doctor will discuss lifestyle changes. These may include:
Surgery and/or endoscopy may be recommended for:
This may be done to stop bleeding. A thin, lighted tube is inserted down the throat into the stomach or intestine. Heat, electricity, epinephrine, or a substance called fibrin glue can then be applied to the area. This should stop the blood flow.
Surgery for duodenal ulcers is rare, but it can greatly reduce acid production. Common procedures include:
To reduce your chance of getting H. pylori infection:
To reduce your chance of getting a duodenal ulcer from NSAIDs:
Last reviewed March 2014 by Daus Mahnke, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.