Microbial Immunity and Immunology

The NYU School of Medicine has a long tradition of excellence in immunology, and this continues to grow.

Current research by existing Division and Affiliated Faculty includes basic mechanisms of protective immunity, mechanisms of immune evasion, and novel mechanisms of vaccine development, and focuses on targets including HIV, tuberculosis, and influenza.

Lung section of C-C chemokine receptor 2 wild-type mouse infected with Mycobacterium tuberculosis.

Three dimensional structure of M. tuberculosis antigen 85B. The epitope recognized by the transgenic T cell antigen receptor of P25-TCR transgenic mice is shown in yellow.

Histopathology of lungs of mice infected for 8 weeks with wild-type (left pane), lipoprotein signal peptidase mutant (center panel), and complemented mutant Mycobacterium tuberculosis

Flow cytometry analysis of mononuclear phagocyte subsets in lungs of mice infected with Mycobacterium tuberculosis.

Translocation of NF-kB (red) to the nucleus (blue) in human macrophages infected with Mycobacterium tuberculosis (green)

Electrophoretic mobility supershift analysis of STAT1 activation in M. tuberculosis-infected macrophages treated with interferon gamma