Vitamin D deficiency (<20 ng/ml) is common, with an estimated prevalence of >20% in adults. While low 25-hydroxy vitamin D levels are associated with cardiovascular disease and suboptimal health, it is unclear whether vitamin D is causally related to disease prevention, or a mere marker of health. Therefore, the association between Vitamin D levels and health outcomes cannot be conflated with a presumed benefit of Vitamin D repletion. Vitamin D repletion may have unintended adverse consequences. We are conducting a placebo-controlled, randomized clinical trial to examine the effect of vitamin D repletion on cholesterol and biomarkers of cardiovascular disease. Vitamin D deficient subjects with risk factors for cardiovascular disease will be randomized to receive either vitamin D3 or placebo for 8 weeks. Compensation is provided.
This study is conducted at The Rockefeller University. Please call 212-327-7631 for more information.
Phone:212-263-7300
